Microcore envision to discover, develop and manufacture clinically validated specialty nutraceuticals, it's driven by a deep core of cutting-edge, innovative and patented technologies. Microcore has evolved, since its inception in 2007 from a research company to a fully-integrated, innovation-led, emerging global Nutraceuticals enterprise committed to reduce therapy costs of chronic conditions like Arthritis, Osteoarthritis, Osteoporosis, Osteo-penia, Inflammatory diseases, Rheumatoid arthritis, Hair and skin care.
Unit-1 R&D infrastructure, Process development and Production facilities are located in Erode the Textile and Turmeric City of South India.(15,000 sqf ) & Unit-2 Asia's largest Egg Shell Membrane processing is under expansion at Tiruchirappalli to Karur at (12 Acres). Microcore in-house R&D is RECOGNIZED by DEPARTMENT OF SCIENTIFIC AND INDUSTRIAL RESEARCH (DSIR) - GVT OF INDIA. Cumulative experiences over 23 years in research, operation and manufacturing remains as catalyst to develop many scientific innovations and scaled up at Industrial scales.
Microcore is one among the very few companies in the world that has the intellectual property rights for Natural Egg Shell Membrane and Un-denatured Collagen Type -II and it remains a pride that Microcore is the first Indian company to receive the functional health claim from CENTRAL/FSSAI/STD/DELHI "Natural Egg Shell Membrane is for Healthy Maintenance of Joints and Connective Tissues". Major business interest of Microcore is in selling the Branded Bio-actives (MUTTAIJOW COMPLEX® | MUTTAI ODU JOW® | AKBACORE® | CUMINCORE® |), Blends, Finished Capsules and Finished Tablets Supported by Scientific Studies. Humbly Microcore is the first company in the world that has conducted comparative clinical studies of Egg Shell Membrane based Nutraceuticals combinations Vs Diacerin based Drug combinations in knee Osteo arthritis patients. |http://jointcore.us/ and supported by regulatory compliances.
It is a great honor to be ranked and chosen amongst an overwhelming number of 37134 nominations filed by SMEs from all over the country and we are delighted to share our happiness with you that MICROCORE is a winner of INDIA SME TOP 100 award 2022
pipelines of Microcore
Microcore's multi-disciplinary team, including scientists, engineers and business
development professionals, have an outstanding track record in turning science into commercially attractive, nutritional solutions, constantly
enriching our unique cluster of technology and expertise. Many innovative combinations
with Natural Egg Shell Membrane
for new indications | Hydroxy
Apatite
| Calcite
| Natural Egg Shell Calcium for
Bone Mineral Density
|
Probiotics rich Egg Albumin
|
Lactobacillus plantarum |
Lactobacillus helveticus
|Lactobacillus salivarius
| Fermented Turmeric
| Dietary Fiber from
BG Husk
|
Anthocyanian from Red Cabbage
| PROTEIN - Fried Bengal Gram
|
Fermented Turmeric
|
Microcore's NESM are branded as MUTTAIJOW COMPLEX® | MUTTAI ODU JOW® Scientifically studied and manufactured without using any chemical and solvent. Microcore NESM is pulled from the inner matrix found inside the egg and it serves as a complex protein molecule that has natural composition of collagen (I,III,V,X), elastin, chondroitin sulfate, glucosamino glycan, hyaluronic acid and many fractional active bio-peptides, it serves as nutrient Powerhouse of numerous Glycosaminoglycans, dermatan and keratan sulphate. It is available at pH range of 7.5 to 9 and also serves an alkaline food and serves in multiple ways to improve health system. These fractional molecules are in complex nature, it helps as Nutraceuticals or health supplement and strongly influence on maintaining healthy joints and connective tissues and help the OA patients. Microcore NESM is approved by FSSAI under 13.6 by FSSAI/STD/Delhi and produced in ISO-22000, GMP and Halal approved facility.
Summary on Clinical Studies of NESM
Worldwide many clinical studies are well documented for the benefits and advantages of NESM. With references to Clinical studies NCT00750477, NCT00750854, NCT00750230, NCT02751944 & CTRI/2021/08/035335 (MICROCORE) these studies consolidated NESM for many health benefits that includes
A randomized, open‑label, multicentered parallel‑group clinical study to evaluate the efficacy and safety of Joint Core TM compared to Jointace DN TM in osteoarthritis patients 2022 Journal of Current Research in Scientific Medicine | Published by Wolters Kluwer Medknow jcrsm_21_22_R2_OA 10.4103/jcrsm.jcrsm_21_22 JOURNAL- DOWNLOAD
(a) Activate level of nuclear factor kappa-light-chain-enhancer of activated B cells ("NF-kB") in the gut of the host helps in NF-kBdys-regulations.
(b) Reduces both early-phase pro-inflammatory cytokines like IL-1β and TNF-α, as well as several other cytokines involved in later phases of the inflammatory process.
(c) Control Liver enzymes in normal ranges alanine transaminase (ALT) & aspartate transaminase (AST).
(d) Helps in treating a non-diseased human having joint stiffness and discomfort.
(e) Helps in treating a human suffering from fibromyalgia.
(f) Eggshell membrane supplementation has been shown to reduce exercise-induced joint pain and stiffness and lower urinary excretion of C-terminal cross-linked telopeptide of type-II collagen (uCTX-II), a marker of cartilage degradation, in healthy, postmenopausal women.
(g) Treatment of Pain and Stiffness Associated with Knee.
(h) Improvement in the appearance of facial skin and hair reduces and or stop the hair fall and hair damages.
(h) Improvement in the appearance of facial skin and hair reduces and or stop the hair fall and hair damages.
(i) Suppression of TNF-α IFN-γ.
(j) Reduced levels of IL-6, IL-10
(k) Works on root cause of Arthritis
New indications of NESM
1. Insulin
Resistance- Improving agent
2. EM exhibits antihyperuricemic effects by promoting renal
urate excretion and regulating renal urate transporters.
Therefore, EM may be useful in the prevention and treatment of
gout and hyperuricemia.
3.Using Eggshell Membrane as Nerve Guide Channels in Peripheral
Nerve Regeneration
4. Eggshell membrane powder lowers plasma triglyceride and liver
total cholesterol by modulating gut microbiota and accelerating
lipid metabolism in high-fat diet-fed mice
5.Study confirms that the NESM helps turnover via the biomarker
C-terminal cross-linked telopeptide of type-II collagen (CTX-II)
versus placebo, evaluated at 1 and 2 weeks of treatment.
Note : NATURAL Egg
Shell Membrane is equivalent to undenatured collagen type -II
The primary endpoint was any statistically significant reduction
in exercise-induced cartilage turnover via the biomarker
C-terminal cross-linked telopeptide of type-II collagen (CTX-II)
versus placebo, evaluated at 1 and 2 weeks of treatment. NEM
produced a significant absolute treatment effect (TEabs) versus
placebo for CTX-II after both 1 week (TEabs −17.2%, P=0.002) and
2 weeks of exercise (TEabs −9.9%, P=0.042). Conclusion NEM
rapidly improved recovery from exercise-induced joint pain (Day
8) and stiffness (Day 4) and reduced discomfort immediately
following exercise (stiffness, Day 7). Moreover, a substantial
chondroprotective effect was demonstrated via a decrease in the
cartilage degradation biomarker CTX-II. Clinical Trial
Registration number: NCT02751944. Decrease in CTX-II illustrates
that the Natural Egg Shell Membrane has the roll and activity to
increase the Collagen type -II of the body requirements, it is
related to the facts that the Membrane fibrillar molecules help
to fix the same.
Ranges of Natural Egg Shell Membrane
Microcore has two ranges of branded Natural Egg Shell membrane that includes Muttaijow Complex ® and Muttaiodu jow ®which are clinically studied. The clinical studies conducted by Microcore entitled as Randomized, open label, multicenter parallel group clinical study to evaluate the efficacy and safety of Joint Core ® in osteoarthritis patients, it illustrates the advantages of Joint Core®. Perhaps it is clinically validated nutraceutical formulations supplemented for Osteoarthritis and Arthritis and manufactured by Microcore Research Labs India Pvt Ltd.
