Microcore envision to discover, develop and manufacture clinically validated specialty nutraceuticals, it's driven by a deep core of cutting-edge, innovative and patented technologies. Microcore has evolved, since its inception in 2007 from a research company to a fully-integrated, innovation-led, emerging global Nutraceuticals enterprise committed to reduce therapy costs of chronic conditions like Arthritis, Osteoarthritis, Osteoporosis, Osteo-penia, Inflammatory diseases, Rheumatoid arthritis, Hair and skin care.

Unit-1 R&D infrastructure, Process development and Production facilities are located in Erode the Textile and Turmeric City of South India.(15,000 sqf ) & Unit-2  Asia's largest Egg Shell Membrane processing is under expansion at Tiruchirappalli  to Karur  at (12 Acres).  Microcore in-house R&D is  RECOGNIZED by DEPARTMENT OF SCIENTIFIC AND INDUSTRIAL RESEARCH (DSIR) - GVT OF INDIA. Cumulative experiences over 23 years in research, operation and manufacturing remains as catalyst  to develop many scientific innovations and scaled up at Industrial scales.

Microcore is one among the very few companies in the world that has the  intellectual property rights for Natural Egg Shell Membrane and Un-denatured Collagen Type -II and it remains a pride that Microcore is the first Indian company to receive the functional health claim from CENTRAL/FSSAI/STD/DELHI "Natural Egg Shell Membrane is for Healthy Maintenance of Joints and Connective Tissues". Major business interest of Microcore is in selling the Branded Bio-actives (MUTTAIJOW COMPLEX^® | MUTTAI ODU JOW^® | AKBACORE^® | CUMINCORE^®), Blends, Finished Capsules and Finished Tablets  Supported by Scientific Studies. Humbly Microcore is the first company in the world that has conducted comparative clinical studies of  Egg Shell Membrane based Nutraceuticals combinations  Vs Diacerin based Drug combinations in knee Osteo arthritis patients http://jointcore.us/ 

It is a great honor to be ranked and chosen amongst an overwhelming number of 37134 nominations filed by SMEs from all over the country and we are delighted to share our happiness with you that MICROCORE  is a winner of  INDIA SME TOP 100 award 2022

Microcore's NESM are branded as MUTTAIJOW COMPLEX^® | MUTTAI ODU JOW^® Scientifically studied and manufactured without using any  chemical and solvent. Microcore NESM is  pulled from the inner matrix found inside the egg and it serves as a complex protein molecule that has natural composition of collagen (I,III,V,X), elastin, chondroitin sulfate, glucosamino glycan, hyaluronic acid and many fractional active bio-peptides, it serves as nutrient Powerhouse of numerous Glycosaminoglycans, dermatan and keratan sulphate. It is available at pH range of 7.5 to 9 and also serves an alkaline food and serves in multiple ways to improve health system. These fractional molecules are in complex nature, it helps as Nutraceuticals or health supplement and strongly influence on maintaining healthy joints and connective tissues and help the OA  patients. Microcore NESM is approved by FSSAI under 13.6 by FSSAI/STD/Delhi and produced in ISO-22000, GMP and Halal approved facility.

Worldwide many clinical studies are well documented for the benefits and advantages of NESM. With references to Clinical studies NCT00750477, NCT00750854, NCT00750230, NCT02751944 & CTRI/2021/08/035335 (MICROCORE) these studies consolidated  NESM for many health benefits that includes

Microcore is the first company that has successfuly completed clinical studies to prove that Natural Egg Shell Membrane based Nutraceuticals combinations are equivalent or better than Diacerin based drug Combinations, for more details pl refer | http://jointcore.us/

A randomized, open‑label, multicentered parallel‑group clinical study to evaluate the efficacy and safety of Joint Core TM compared to Jointace DN TM in osteoarthritis patients  2022 Journal of Current Research in Scientific Medicine | Published by Wolters Kluwer  Medknow jcrsm_21_22_R2_OA 10.4103/jcrsm.jcrsm_21_22  JOURNAL- DOWNLOAD

(a) Activate level of nuclear factor kappa-light-chain-enhancer of activated B cells ("NF-kB") in the gut of the host helps in NF-kBdys-regulations.

(b) Reduces both early-phase pro-inflammatory cytokines like IL-1β and TNF-α, as well as several other cytokines involved in later phases of the inflammatory process.

(c) Control Liver enzymes in normal ranges alanine transaminase (ALT) & aspartate transaminase (AST).

(d) Helps in treating a non-diseased human having joint stiffness and discomfort.

(e) Helps in treating a human suffering from fibromyalgia.

(f) Eggshell membrane supplementation has been shown to reduce exercise-induced joint pain and stiffness and lower urinary excretion of C-terminal cross-linked telopeptide of type-II collagen (uCTX-II), a marker of cartilage degradation, in healthy, postmenopausal women.

(g) Treatment of Pain and Stiffness Associated with Knee.

(h) Improvement in the appearance of facial skin and hair reduces and or stop the hair fall and hair damages.

(i) Suppression of TNF-α  IFN-γ.
(j) Reduced levels of IL-6, IL-10

1. Insulin Resistance- Improving agent
2. EM exhibits antihyperuricemic effects by promoting renal urate excretion and regulating renal urate transporters. Therefore, EM may be useful in the prevention and treatment of gout and hyperuricemia.
3.Using Eggshell Membrane as Nerve Guide Channels in Peripheral Nerve Regeneration
4. Eggshell membrane powder lowers plasma triglyceride and liver total cholesterol by modulating gut microbiota and accelerating lipid metabolism in high-fat diet-fed mice
5.Study confirms that the NESM helps turnover via the biomarker C-terminal cross-linked telopeptide of type-II collagen (CTX-II) versus placebo, evaluated at 1 and 2 weeks of treatment.

Note : NATURAL Egg Shell Membrane is equivalent to undenatured collagen type -II The primary endpoint was any statistically significant reduction in exercise-induced cartilage turnover via the biomarker C-terminal cross-linked telopeptide of type-II collagen (CTX-II) versus placebo, evaluated at 1 and 2 weeks of treatment. NEM produced a significant absolute treatment effect (TEabs) versus placebo for CTX-II after both 1 week (TEabs −17.2%, P=0.002) and 2 weeks of exercise (TEabs −9.9%, P=0.042). Conclusion NEM rapidly improved recovery from exercise-induced joint pain (Day 8) and stiffness (Day 4) and reduced discomfort immediately following exercise (stiffness, Day 7). Moreover, a substantial chondroprotective effect was demonstrated via a decrease in the cartilage degradation biomarker CTX-II. Clinical Trial Registration number: NCT02751944. Decrease in CTX-II illustrates that the Natural Egg Shell Membrane has the roll and activity to increase the Collagen type -II of the body requirements, it is related to the facts that the Membrane fibrillar molecules help to fix the same.
 

Ranges of Natural Egg Shell Membrane

Microcore has two ranges of branded Natural Egg Shell membrane that includes Muttaijow Complex ^® and Muttaiodu jow ^®which are clinically studied. The clinical studies conducted by Microcore entitled as Randomized, open label, multicenter parallel group clinical study to evaluate the efficacy and safety of Joint Core ^® in osteoarthritis patients, it illustrates the advantages of Joint Core^®. Perhaps it is clinically validated nutraceutical formulations supplemented for Osteoarthritis and Arthritis and manufactured by Microcore Research Labs India Pvt Ltd.