Hydroxyapatite is a calcium phosphate ceramics material that is found to be very crucial as a biomaterial because of its osteophilic nature and its incorporation into bone tissues. Hydroxyapatite (HA) which compose around 70 % of human bone is an example of bioactive ceramics most commonly used in bone implantation. Because of their excellent bioactivities, hydroxyapatites are regarded as attractive biomedical materials. Hydroxyapatite (HA) is a particularly attractive material for bone and tooth implants since it closely resembles human tooth and bone mineral and has proven to be biologically compatible with these tissues. Hydroxyapatite, HA is an elementary calcium phosphate, and its chemical formula is Ca10(PO4)6(OH)2 present as main material of teeth, bones and mineral certainly with high bio-affinity. It is composite by below methods, and it is also applicable in various fields including biomaterials. In the meantime, amorphous HA is no longer stable and could dissolve reliant on usage environment; a sintered body has been effectively used as a material in general. And, the sintered body could not dissolve so much owing to its high crystalline. Because fusion and grain growth of each particle arose on its process stage are foreseeable, it has been hard to control configuration and grain diameter on a nanoscale impartial like initial particles of amorphous HA. The synthesis of HA, with its numerous morphologies, structures, and textures, has enthusing a prodigious deal of interest in academic and industrial research for numerous heterogeneous catalysis applications. In the past three decades, a numerous synthetic routes for producing HAp powders have been developed.