Research is the fundamental aspects of Microcore

Research is the fundamental aspects of Microcore

R&d Activities

Research and Development (R&D) plays a crucial role in Microcore's vision and strategy since its incorporation in 2007. R&D is stated as a fundamental part of Microcore's vision and strategy right from its inception in 2007. This implies that the company places a strong emphasis on innovation and staying at the forefront of technological advancements in biotechnology. Microcore leverages its expertise in biotechnology to create novel processes and develop new molecules specifically in the field of nutraceuticals. This suggests a focus on health and wellness products derived from natural sources.Microcore highlights its commitment to continuous investment in R&D. This ongoing investment is crucial for staying ahead of the curve, adapting to industry changes, and ensuring the development of cutting-edge solutions. Innovative Processes, Products, Technologies, and IPR: The outcome of Microcore's R&D efforts includes the development of innovative processes, products, technologies, and Intellectual Property Rights (IPR). This suggests a holistic approach to innovation, covering various aspects that contribute to the company's success and differentiation in the market. Microcore's commitment to R&D, coupled with its focus on biotechnology and nutraceuticals, positions the company as a forward-thinking and innovative player in its industry. Continuous investment in R&D reflects a dedication to staying competitive and leading the way in the development of new solutions and technologies.

 

In-house R&D has been recognized by the Department of Scientific and Industrial Research (DSIR) in the Government of India. This acknowledgment reflects the quality and significance of your research efforts. Your approach of defining core competencies aligned with major technology platforms, especially in the field of Nutraceuticals, showcases a strategic focus. Being able to apply these competencies to product development, process technologies, and scale-up indicates a comprehensive approach to innovation. The S2B (Science to Business) and B2S (Business to Science) approach you've mentioned is an effective strategy. Transitioning knowledge and insights from scientific research to practical business applications and vice versa helps bridge the gap between theoretical advancements and market demands. This not only demonstrates a strong understanding of market dynamics but also positions your organization well to meet industry needs.

 

R&d - Pipeline Molecules


 

Microcore's multi-disciplinary team, including scientists, engineers and business development professionals, have an outstanding track record in turning science into commercially attractive, nutritional solutions, constantly enriching our unique cluster of technology and expertise. Some of our pipeline product includes | Wound healing Collagen Complex | Hydroxy Apatite for dental procedures and bone surgery| High PDAACS protein from  Fried Bengal Gram | Vitamin K27 from fermented Fried Bengal Gram  | Medium-chain triglycerides (MCTs) from fermented Coconut oil Fermented Turmeric | Soluble Dietary Fiber from BG Husk | Anthocyanian from Red Cabbage

 


 

Discovery Research

Microcore has a robust focus on microbial research and development, particularly in the field of microbiome modulators and their applications in preventing and managing chronic lifestyle diseases. Your proprietary collection of over 3000 micro-organisms, along with a strain and molecule database for probiotics, enzymes, and biotransformation, highlights a comprehensive approach to discovering and screening microbial strains. The emphasis on classical mutation and molecular biology as core competencies for strain and yield development suggests a sophisticated understanding of genetic and molecular mechanisms. This foundation likely plays a crucial role in Microcore's ability to identify and develop microbial strains, compounds, and formulations for use in food ingredients, supplements, and active compounds with potential health benefits.Your focus on chronic lifestyle diseases such as obesity, hypercholesterolemia, lipid profiles, urea, uric acid, and diabetes indicates a commitment to addressing major health challenges. The established pipeline of microbiome modulators suggests ongoing efforts to advance research and development in this area, potentially leading to innovative solutions for improving human physiology and overall health.Microcore is actively engaged in cutting-edge research and development, leveraging a combination of traditional microbiology techniques and molecular biology advancements to contribute to the prevention and management of chronic diseases.

Microcore's Leuconostoc mesenteroides sub species idlies

Next-generation probiotic that aids soft and nutritious idli fermentation.

Microcore's Lactobacillus sweeticus

Produces fruity aroma (pine apple and jack fruit flavor) flavoring agents in food preparations.
Next-generation probiotic that aids soft and nutritious idli fermentation.

Microcore's Lactobacillus plantarum

Next-generation probiotic that aids elements of cardiovascular and well being. Its outstanding ability to modulate bile acid metabolism is beneficial for heart health factors such as high blood pressure and high cholesterol, as well as other processes from liver function to glucose regulation and vitamin metabolism.

Microcore's Lactobacillus fermentum

Boosts production of the major cellular antioxidant glutathione.

Microcore's Lactobacillus helveticus

Works for bone health (prevention of osteoporosis), sport nutrition, or dental health. Suitable for use in food supplement form, or as fermentation starter for functional dairy products. It stimulates absorption and transport of calcium by intestinal cells, and favors its assimilation by the organism. It can be used for several applications including bone health (prevention of osteoporosis), sport nutrition, or dental health.
 

Journals & Publications

 

Medical-Journals

1. A randomized, open‑label, multicentered parallel‑group clinical study to evaluate the efficacy and safety of Joint Core® compared to Jointace DN® in osteoarthritis patients  2022 Journal of Current Research in Scientific Medicine | Published by Wolters Kluwer  Medknow jcrsm_21_22_R2_OA 10.4103/jcrsm.jcrsm_21_22  |

JOURNAL DOWNLOAD

 

2."COMPARATIVE EVALUATION OF BIOAVAILABILITY, EFFICACY AND SAFETY OF MICROCORE NESC® WITH CALCIUM CARBONATE AND CALCIUM CITRATE MALATE IN OSTEOPENIC AND OSTEOPOROTIC PATIENTS - A RANDOMIZED CLINICAL TRIAL", has been accepted for publication in Indian Journal of Orthopaedics. Indian Journal of Orthopaedics Received: 29 November 2023 / Accepted: 30 January 2024
 Indian Orthopaedics Association 2024  www.eggcalcium.com | https://link.springer.com/article/10.1007/s43465-024-01117-3
 

Biotech-Journals

1.Evaluation of TRICHONEM TM as Anti-Dandruff and Hair growth promoter in young adults - Research J. Topical and Cosmetic Sci. 13(2): July - December, 2022

 

2.Evaluation of NEMBUTY TM for Anti-wrinkling, Anti-ageing and Moisturizing Face Pack for Various Skins - Dermatology and Dermatitis {approved under press}
 

3.Effects on Oral Supplementation of Nutraceuticals formulations- Trichovitals TM in young adults for healthy maintenance of hair growth.  Research Journal of Topical and Cosmetic Sciences (RJTCS) Vol. 13 Issue 1, January - June 2022.

 

4. Effects of Oral Supplementation of Muttaijow complexTM on Human Skin, Hair and Nail Physiology. Research Journal of Topical and Cosmetic Sciences Vol. 12 | Issue-01|January - June | 2021

5.Effects of Oral Supplementation of Human TrichovitalsTM Skin, Hair and Nail Physiology Research Journal of Topical and Cosmetic Sciences Vol. 12 | Issue-01|January - June | 2021

6. Bioactive molecule composition of natural egg membrane concentrate (NEMC TM ) vs. soluble egg membrane (SEM) International Journal of Biotechnology & Biochemistry (IJBB) ISSN 0973-2691 Volume 16, Number 1 (2020) pp. 25

 

7. Water Insoluble Hydro-Albumen Gel Crystals From Raw Egg And Its Albumen Application : 71760-IJABR

8. Enzymatic Methods To Produce Residue Free Sago For High Gell Foods And Process Thereof : 71761-IJAFST

9. Recovery Of Albumin And Yolk Contents From Waste Of Raw Egg Processing : 71762-IJBB

10. Roasted Bengal Gram Protein For Low Molecular Mass With High Solubility And Digestibility : 71763-IJABB

11. Shake Flask Studies On Ethanol Production From Hydrolyze Bagasse And Egg Albumin Waste By Using Enzymes And Chemicals : 71766 - IJABB

12. Garlic Peel And Hsuk As A Potential Source Of Insoluble Dietary Fibers For High Hydrophilic And Liphophilic Activity:- Paper Code #: Rip - 71767 - IJAFST

13. Screening and processing industrial agro wastes for insoluble dietary fibers and microcrystalline cellulose. International Journal of Agriculture and Food Science Technology. ISSN 2249-3050 Volume 11, Number 1 (2020), pp. 1-16

14. Ozone modified starch and its application in yarn sizing and advantages. International Journal of Chemistry and Applications. ISSN 0974-3111 Volume 12, Number 1 (2020), pp. 1-11

15. Isolation and Extraction of Curcumin from Three Different Varieties of Curcuma longa - A Comparative Study. International Journal of Pharmaceutical Research Allied Sciences. Volume 4, Issue 2 (2015):79 -84

16. Production of ω-3-Docosahexanoic Acid (DHA) by Using Oleaginous Marine Algae International Journal of Applied Biotechnology and Biochemistry. ISSN 2248-9886 Volume 4, Number 1 (2014) pp. 15-24

17. Miniaturized Screening and Isolation of Phospholipase A2 Rhizopus by using egg yolk substrate. International Journal of Applied Biotechnology and Biochemistry (IJABB) ISSN 2248-9886 Volume 3,Number 1(2013) pp. 83-96

18. Production of Fruity Aroma by Non Lactose Fermenting Lacto bacilli Species Isolated from South India Hills. International Journal of Applied Biotechnology and Biochemistry Volume 2, Number 4 (2012) pp. 319-326

19. Conversion of egg shell waste in to dicalcium phosphate. Global Journal of Biotechnology and Biochemistry Research (GJBBR). ISSN 2248-9894 Volume 2, Number 1 (2012), pp. 11-16

20. Miniaturized screening and isolation of Oleaginous fungi from low temperature environment. International Journal of Advanced Biotechnology Research (IJABR). ISSN 2249-3166 Volume 2, Number 1 (2012), pp. 29-34

21. In Vitro Cytotoxic Effects of Muntingia Calabura Linn. Fruits against Human Cancer Cell Lines, International Journal of Biotechnology and Biochemistry. Volume 7 Number 3 (2011) pp. 379-384

22. Phytochemical Studies on Muntingia Calabura L. Fruits from Tamil Nadu, India. International Journal of Biotechnology and Biochemistry. Volume 7 Number 3 (2011) pp. 311-320

23. Hepatoprotective Effect of Muntingia Calabura Fruit Extracts Against Paracetamol Induced Oxidative Stress in Wistar Albino Rats. International Journal of Biotechnology and Bioengineering Research. Volume 2 Number 1 (2011) pp. 21-27

24. Recycling Organic Waste and Composting at Direct Plantain Field for the cost effective production of biofertilizer and application studies at Tiruchirapalli District of South India. International Journal of Applied Agricultural Research. Volume 5 Number 3 (2010) pp. 337-342

25. Effective Utilization of Tapioca Fiber Wastes to Improve Methane Production. International Journal of Applied Environmental Sciences, Volume 5, Number 3 (2010), pp. 327-330

26. Study of Diacyl Glycerides Profile and Content in Cooking Oils using Thin Layer Chromatography and Gel Permeation Chromatography. International Journal of Biochemistry and Biotechnology (IJBB) Volume 6, Number 1 (2010), pp. 35 -44

27. Optimizing Dosage of Organic Fertilizer Fermented Fish Liquid Protein Hydrolysate for Eradication of Stunted Growth in Paddy Cultivation and Yield Improvement. International Journal of Applied Agricultural Research (IJAAR), Volume 4, Number 3 (2009), pp. 222-229

28. Field Studies of Paddy Cultivation using Organic Fertilizer produced from Fish-Protein Hydrolysate. International Journal of Applied Agricultural Research (IJAAR), Volume 4, Number 1 (2009), pp. 29-35

29. Screening and Purification of Agro-Processing Wastes for the Production of Dietary Fibers. Poster presentation 20th Indian Convention of Food Scientist and Technologists (ICFOST 2009). Receipt of best poster award at ICFOST 2009

 

Acknowledgement

1. Formulation, characterization and antibacterial activity evaluation of collagen based Silver nanoparticle, International Journal of Pharmaceutical Science and Research.  IJPSR 2020 Volume 11 (4), 1735-1739