Microcore's Natural Undenatured Chicken Sternum Collagen Complex II and Undenatured Collagen Type-II are made from chicken sternum grown by backward integration. It is produced from ISO-22000,GMP, FSSAI/CL, HALAL certified and by Patent Granted Technologies. The specialty is that it contains integrated epitope or antigencity. Undenatured Collagen II make Dendritic cells (DCs) in GALT take it up in its glycosylated form. This makes T helper cells recognize the antigen epitopes, inducing an initial mild immune response and then gradually developing ORAL TOLERANCE thereby attenuating the immune response against cartilage collagen II. This stimulates T regulatory cell and suppresses T helper cell stimulation and response therefore, endogenous collagen synthesis, or collagen peptide supplementation can be more effective once inflammatory cartilage collagen destruction is suppressed. Microcore's Undenatured collagen is supplied only as formulated product or finished product and it is not supplied as independent ingredient.