UD-Core-II®
UDCORE-ii, which is Microcore's Undenatured Chicken Sternum Collagen Complex II. This product is derived from chicken sternum through a backward integration process and is produced using various certifications such as ISO-22000, GMP, FSSAI/CL, HALAL, and Kosher. The key feature of UDCORE-ii ®is its integrated epitope or antigencity. Undenatured Collagen Type-II has a specific mechanism of action. It is designed to be taken up by Dendritic cells (DCs) in the Gut-Associated Lymphoid Tissue (GALT) in its glycosylated form. This process allows T helper cells to recognize the antigen epitopes, leading to an initial mild immune response. Over time, this can contribute to the development of oral tolerance, which means the immune response against cartilage collagen II is attenuated. The gradual development of oral tolerance is crucial in suppressing the immune response against collagen II. This stimulation of T regulatory cells and suppression of T helper cell response can ultimately lead to the effective suppression of inflammatory cartilage collagen destruction. As a result, the synthesis of endogenous collagen or supplementation with collagen peptides becomes more effective once the immune response is adequately suppressed. The use of patent-granted technologies in the production of UDCORE-ii adds to its uniqueness and potentially enhances its effectiveness in promoting oral tolerance and addressing issues related to cartilage collagen destruction. It's worth noting that this information is specific to the details you provided and may be subject to further scientific research and development.
Microcore's Undenatured Chicken Sternum Collagen Complex II and Undenatured Collagen Type-II are made from chicken sternum grown by backward integration. It is produced from ISO-22000,GMP, FSSAI/CL, HALAL certified and by Patent Granted Technologies. The specialty is that it contains integrated epitope or antigencity. Undenatured Collagen II make Dendritic cells (DCs) in GALT take it up in its glycosylated form. This makes T helper cells recognize the antigen epitopes, inducing an initial mild immune response and then gradually developing ORAL TOLERANCE thereby attenuating the immune response against cartilage collagen II. This stimulates T regulatory cell and suppresses T helper cell stimulation and response therefore, endogenous collagen synthesis, or collagen peptide supplementation can be more effective once inflammatory cartilage collagen destruction is suppressed. UD-Core-II® is supplied only as formulated product or finished product and it is not supplied as independent ingredient.
